[Effects of scalp catgut embedding on SOD, NO, MDA in the rat with Parkinson's disease].

Objective To explore the mechanism of scalp catgut embedding for treatment of Parkinson′s disease. Methods Parkinson′s disease model rats were prepared, and randomly divided into a model group, scalp acupuncture group, medication group, with a control group set up. The scalp acupuncture group were treated with catgut embedding at "the chorea-trembling conroued area" lateral to "Baihui" (GV 20) and the medication group with intragastric perfusion of L-dopa suspension. After treatment for 30 days, behavior indexes were investigated and malondialdehyde (MDA) and nitric oxide (NO) contents and superoxide dismutase (SOD) activity in the brain were detected. Results MDA content in the brain of the model rats were significantly decreased (P0.01), NO level significantly increased (P0.05) by scalp catgut embedding, with no significant change of SOD activity (P0.05); and the behavior indexes and tissue and form of the brain had significant improvement. Conclusion Scalp catgut embedding has regulative action on anti-oxidant enzyme system in the Parkinson′s disease rats, has significant improvement of cells, tissues and form of the brain.