Control of IBMIR Induced by Fresh and Cryopreserved Hepatocytes by Low Molecular Weight Dextran Sulfate versus Heparin

Elisabet Gustafson,Sana Asif,Huda Kozarcanin,Graciela Elgue,Staffan Meurling,Kristina Nilsson-Ekdahl,Bo Nilsson

Control of IBMIR Induced by Fresh and Cryopreserved Hepatocytes by Low Molecular Weight Dextran Sulfate versus Heparin

2017

Elisabet Gustafson
Sana Asif
Huda Kozarcanin
Graciela Elgue
Staffan Meurling
Kristina Nilsson-Ekdahl
Bo Nilsson

Rapid destruction of hepatocytes after hepatocyte transplantation has hampered the application of this procedure clinically. The instant blood-mediated inflammatory reaction (IBMIR) is a plausible ...

Keywords:

Immunology
Heparin
Cryopreservation
Low molecular weight dextran
Innate immune system
Sulfate
Diabetes mellitus
Biology
Hepatocyte transplantation
dextran sulfate
Inflammation

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