Asymmetric α-Pentadienylation of Aldehydes with Cyclopropylacetylenes.
2021
By employing readily available cyclopropylacetylene and its derivatives as the pentadienylation reagent, an asymmetric regioselective asymmetric α-pentadienylation reaction of aldehydes is developed by cooperative catalysis of a chiral Pd(0) catalyst and a chiral Bronsted acid in the presence of a subschoichmetric amount of an achiral amine. α-Pentadienylated aldehydes are afforded with high yields and enantioselectivities as well as excellent E/Z ratios.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
71
References
3
Citations
NaN
KQI