The effectiveness of intramuscular biperiden in acute akathisia: a double-blind, randomized, placebo-controlled study.

AbstractNeuroleptic-induced acute akathisia (NIA) is a distressing condition and an important clinical problem because it is associated with treatment noncompliance and suicidal or impulsive behavior. Anticholinergics are among the treatment options; however, a review of the literature fails to iden