Efficiency and safety of varying the frequency of whole blood donation: randomised trial of 45,000 donors

EDA received research funding from the UK Medical Research Council, British Heart Foundation, National Institute for Health Research, and NHSBT during the conduct of the study. SGT received grants from the UK Medical Research Council, British Heart Foundation, National Institute for Health Research, and NHSBT during the conduct of the study. SK received grants from the UK Medical Research Council, British Heart Foundation, National Institute for Health Research, and NHSBT during the conduct of the study. JD has received research funding from the UK Medical Research Council, British Heart Foundation, National Institute for Health Research, NHSBT, European Commission, European Research Council, Merck Sharpe & Dohme UK, Biogen, Novartis, Pfizer, Merck, and Wellcome Trust during the conduct of the study. All other members of the writing committee declare no competing interests. The trial was funded by NHSBT and the NIHR Blood and Transplant Research Unit in Donor Health and Genomics (NIHR BTRU-2014-10024). The trial’s coordinating centre at the Department of Public Health and Primary Care at the University of Cambridge, Cambridge, UK, has received core support from the UK Medical Research Council (G0800270), British Heart Foundation (SP/09/002), and the NIHR Cambridge Biomedical Research Centre. Investigators at the University of Oxford, Oxford, UK, have been supported by the Research and Development Programme of NHSBT, the NHSBT Howard Ostin Trust Fund, and the NIHR Oxford Biomedical Research Centre through the programme grant NIHR-RP-PG-0310-1004.