Usefulness of three SOS-response tests for genotoxicitydetection.
2007
The RecA test, a luminescence SOS reporter test, and two
well-known SOS reporter assays, umuC test and SOS chromotest,
were compared. The main point of this study was to indicate the
sensitivity of these tests. This was on the basis of comparison
of effects on standard mutagens and environmental samples. The
results with the selected chemicals showed that the RecA test
was less sensitive in a qualitative way, in com-parison to the
umuC test. However, its responses were quite comparable with
the SOS chromotest. Results suggest that for our choice of
environmental samples and chemical stan-dards the umuC test is
optimal for genotoxicity detection, in comparison to RecA test
and SOS chromotest.
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