Practical Guide to Performing High Volume Hemodiafiltration

The achievement of high volumes in online hemodiafiltration seems mandatory to obtain clinical benefit of the treatment. As of yet, evidence suggests that practice patterns rather than patient characteristics determine convection volume. The most important determinants of convection volume are treatment time, blood flow rate, and probably filtration fraction. Hematocrit plays a minor role. In this chapter, the treatment related factors are discussed in detail.