Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp.

Ikuma Kuroda,Musri Musman,Ikuko I. Ohtani,Toshio Ichiba,Junichi Tanaka,Dolores Garcia Gravalos,Tatsuo Higa

Pachastrissamine, a Cytotoxic Anhydrophytosphingosine from a Marine Sponge, Pachastrissa sp.

2002

Ikuma Kuroda
Musri Musman
Ikuko I. Ohtani
Toshio Ichiba
Junichi Tanaka
Dolores Garcia Gravalos
Tatsuo Higa

An anhydrophytosphingosine named pachastrissamine (3) has been isolated as a cytotoxic principle of a sponge, Pachastrissa sp., and the structure including the absolute configuration determined by spectroscopic and chemical analysis.

Keywords:

Absolute configuration
Stereochemistry
Pachastrissa
Cytotoxic T cell
Sponge
Pachastrissamine
Biochemistry
Pharmacognosy
Organic chemistry
Chemistry
animal origin

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