Letter Regarding Article by Sawhney et al, “Treatment of Left Anterior Descending Coronary Artery Disease With Sirolimus-Eluting Stents”

To the Editor: Sawhney et al1 describe a superior adverse cardiac event rate of 9.8% with sirolimus-eluting stents (SES) versus 24.9% with bare metal stents in left anterior descending coronary artery (LAD) disease after 1-year follow-up. Their subgroup analysis of patients with isolated proximal LAD lesions (29.3%) shows similar results because of a reduced in-stent restenosis rate after SES.1 They conclude that long-term SES results might be similar to those of surgically treated LAD lesions.1 Until now, the major randomized SES studies (RAVEL and SIRIUS) reported superior results after SES compared with bare metal stents in less complex lesions. Being a SIRIUS substudy, the article by Sawhney et …