A novel HLA-A*29 allele (A*2916) of a Caucasian relative to an ALL patient containing a point mutation in a putatively conserved region which was identified through the loss of a specific amplificate in a low-resolution SSP-PCR kit
2007
Summary
A novel HLA-A29 (HLA-A*2916) allele has been identified in a Caucasian man from Middle Europe using single-allele-specific sequencing strategy. This allele is identical to the HLA-A*29010101 allele except for one point mutation in the putatively conserved codon 128 (GAGCAG) resulting in an amino acid exchange from glutamic acid (E) to glutamine (Q).
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KQI