Method for preparing 3-[1-(dimethylamino)ethyl]phenol

2015 
The invention provides a method for preparing 3-[1-(dimethylamino)ethyl]phenol II. According to the method, by the following reaction formula shown in the description, 3-[1-(methylamino)ethyl)phenol III is prepared from meta-hydroxyl acetophenone IV, which serves as a raw material, through leuckart reaction and is subjected to eschweiler-clarke reaction so as to obtain 3-[1-(dimethylamino)ethyl]phenol II. The method provided by the invention has the advantages that the synthesis route is short, the raw material is cheap and easily available, hazardous and noxious substances are not required to be used, the operation is easy, the production cost is low, and the problems such as complicated reaction operation, high cost, low yield and the like in the prior art are solved. The method is applicable to industrial production and has a relatively high application value.
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