studies in the relationship between molecular structure and chromatographic behaviour—III: Mechanism of the reversed-phase chromatography of some alkyl phenols

Abstract It can be shown that thin-layer chromatography by the reversed-phase technique gives results which are sufficiently reproducible for correlation of Chromatographie behaviour with chemical structure to be attempted. To a first approximation the Martin additivity principle is valid, but variations in the intermolecular forces between solute molecules and solvent molecules, caused by the easy transmission of electronic effects through an aromatic system, result in deviations from ideal conditions.