Abstract 17655: Psoas Muscle Area and Body Mass Index Are Associated With Long-Term All-Cause Mortality After Transcatheter Aortic Valve Replacement

Introduction: Measures of sarcopenia and obesity, like the computed tomography (CT)-derived psoas muscle area (PMA) and body mass index (BMI), are related to short-term survival after transcatheter aortic valve replacement (TAVR), but impact on long-term outcomes has not been established. The purpose of this study is to evaluate long-term predictive value of PMA and BMI in TAVR patients. Methods: The PMA (cm2) at the level of L4 was measured on non-contrast planning CTs (Fig. A) of consecutive patients who underwent TAVR from 2008-2016. PMA and BMI (kg/m2) were tested for associations with all-cause mortality at 1- and 2- year follow-up, adjusting for Society of Thoracic Surgeons (STS) risk score. Further, PMA and BMI were dichotomized to identify sarcopenic and lean individuals (PMA: males: < 23.1 cm2; females: < 16.4 cm2, and BMI < 24.3 kg/m2). STS-adjusted survival analysis determined hazard ratios compared to the rest of the population. Survival differences were tested with log-rank test at 1- and 2-y...