Estimating the Time to Benefit for Preventive Drugs with the Statistical Process Control Method: An Example with Alendronate

Esther M.M. van de Glind,Hanna C. Willems,Saeid Eslami,Ameen Abu-Hanna,Willem F. Lems,Lotty Hooft,Sophia E. de Rooij,Dennis M. Black,Barbara C. van Munster

Estimating the Time to Benefit for Preventive Drugs with the Statistical Process Control Method: An Example with Alendronate

2016

Esther M.M. van de Glind
Hanna C. Willems
Saeid Eslami
Ameen Abu-Hanna
Willem F. Lems
Lotty Hooft
Sophia E. de Rooij
Dennis M. Black
Barbara C. van Munster

Background For physicians dealing with patients with a limited life expectancy, knowing the time to benefit (TTB) of preventive medication is essential to support treatment decisions.

Keywords:

Control chart
Randomized controlled trial
Physical therapy
Bone density
Survival analysis
Life expectancy
Statistical process control
Absolute risk reduction
Medicine
preventive medication
Pharmacotherapy
treatment decision making
Alternative medicine

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