Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy.

Background Leukocyte depletion at the time of transplantation with alemtuzumab (Campath-1H) has been demonstrated to be a potential strategy for reducing long term exposure to immunosuppressive drugs. While the impact of alemtuzumab treatment on the immune system has been explored, the effects of long-term immunosuppressive therapy in alemtuzumab treated patients still need to be elucidated.