Clinical course of post transfusion in a patient with anti Sda antibody positive femur fracture.

A 73-year-old man was admitted to our hospital for femur fracture by traffic accident. Anti Sda antibody was detected in his serum by the examination for transfusion. Thirty-three units of RBCs, which were Sda positive, were given over three days on operation and post operation period. About two weeks later, the titer of anti Sda antibody rose from ×4 to ×128. The activity of his serum lactic dehydrogenase was 531U/1. Total serum bilirubin concentration was 1.5mg/dl. Reticulocyte count was 24‰. Occult blood in urine became positive. Although clinical symptom of hemolytic transfusion reaction was not obviously recognized, the clinical laboratory data might exhibit mild in vivo hemolysis of transfused RBCs.