The potential protein-mediated hepatic uptake: discussion on the molecular interactions between albumin and the hepatocyte cell surface and their implications for the in-vitro-to-in vivo extrapolations of hepatic clearance of drugs
2019
ABSTRACTIntroduction: In quantitative modeling, the resolving of underpredictions and overpredictions of hepatic clearance (CLh) makes a top priority for pharmacokinetic modelers. Clearly, the ‘pro...
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