Preserved Renal Allograft Function and Successful Treatment of Metastatic Merkel Cell Cancer Post Nivolumab Therapy

Checkpoint inhibitors like programmed cell death-1 (PD1) are changing the way we envisage the prognostication of metastatic carcinomas. Binding of PD1 to PD1-ligand unleashes the power of naturally occurring antitumor T cells by suppressing T-cell migration, proliferation, and cytotoxic activities.1