MP59-09 ANTI-FIBROTIC EFFECT OF EVEROLIMUS IN RENAL ALLOGRAFT VIA REGULATION OF MTOR-RELATED PROTEIN EXPRESSION

Shun Nishioka,Takahito Endo,Naoki Yokoyama,Teruyuki Oda,Satoshi Ogawa,Takeshi Ishimura,Junya Furukawa,Ken-ichi Harada,Katsumi Shigemura,Nobuyuki Hinata,Yuzo Nakano,Masato Fujisawa

MP59-09 ANTI-FIBROTIC EFFECT OF EVEROLIMUS IN RENAL ALLOGRAFT VIA REGULATION OF MTOR-RELATED PROTEIN EXPRESSION

2020

Shun Nishioka
Takahito Endo
Naoki Yokoyama
Teruyuki Oda
Satoshi Ogawa
Takeshi Ishimura
Junya Furukawa
Ken-ichi Harada
Katsumi Shigemura
Nobuyuki Hinata
Yuzo Nakano
Masato Fujisawa

INTRODUCTION AND OBJECTIVE:Although several clinical studies have reported that everolimus (EVR) has a favorable effect on kidney allografts, the pathophysiological mechanism remains unclear. In th...

Keywords:

anti fibrotic
PI3K/AKT/mTOR pathway
Everolimus
Protein expression
renal allograft
Pathology
Medicine

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