Results of the feasibility stage of stampede: A multiarm, multi-stage phase II/III trial for patients with high risk prostate cancer (ISRCTN78818544)

Most drug trials in prostate cancer (PCa) concentrate on patients withhormone refractory disease. Drugs which work later in the disease may work better still if used earlier. STAMPEDE is an academic, investigator-initiated randomised controlled trial to test six treatment approaches for patients with high-risk localised or metastatic PCa who are commencing long-termhormone therapy (HT).