418 Inhibition of IGF1R with Ganitumab Switches Pancreatic Cancer Cells to Oxidative Metabolism

S. Chandarlapaty, V. Rodrik-Outmezguine, M. Maurizio Scaltriti, R. Sakr, M. Will, D. Giri, C. Hudis, J. Baselga, T. King, N. Rosen. Memorial Sloan-Kettering Cancer Center, Human Oncology and Pathogenesis Program, New York, USA; Memorial Sloan-Kettering Cancer Center, Molecular Pharmacology, New York, USA; Massachusetts General Hospital Cancer Center, Medicine, Boston, USA; Memorial Sloan-Kettering Cancer Center, Surgery, New York, USA; Memorial Sloan-Kettering Cancer Center, Pathology, New York, USA; Memorial Sloan-Kettering Cancer Center, Medicine, New York, USA