Irritable Bowel Syndrome and Early Life Trauma Are Associated With an Enhanced HPA Axis Response to Hormone Stimulation

G A A b st ra ct s group. Only 37% of the PPI group had documented indication for PPI use. Conclusions: SBP is common problem with cirrhotic patients. There are many risk factors associated with developing SBP, and one of these may be the use of PPIs. Our study found that the use of PPIs and lower ascitic albumin level may predispose patients to more severe infections and increase mortality. This is an important consideration when prescribing PPIs in cirrhotic patients.