The pathogenetic significance of antioxidant properties of middle molecular weight peptides in thermal burns

: Antioxidative activity of middle mass peptides (MMP), obtained from blood of dogs with burns and of intact animals, was studied. "Lowry-chromogenic" amino acids containing in the MMP structure were responsible for the antioxidative activity. At the same time, this property of MMP was related also to their pathogenecity. The peptides were able to regulate lipid peroxidation in rats with thermic burns. Regulating effects of MMP on lipid peroxidation in pathogenesis of burns are discussed.