FRI0071 Does psychological status drive patient global assessment for rheumatoid arthritis patients who do not have any clinical signs of inflammation? an exploratory analysis of near-remission using the rheumatoid arthritis impact of disease (RAID) score.

Background Patients reaching remission for joint counts and CRP according to the ACR/EULAR Boolean definition fo remission (value Objectives To assess whether psychological components of the RAID score explain the elevated PGA for patients in near-remission. Methods The RAID database, based on an international multicenter cross-sectional study of consecutive RA patients from 12 European countries, was used (3). Each component of the RAID score ranges from 0 (no impact) to 10 (high impact). Patients in near-remission were compared to those in remission and not in remission for the proportion of patients with a score Results In total, 359 patients had complete data for this analysis: mean (±standard deviation) age 55.8±13.0 yrs, disease duration 12.6±10.5 yrs, 76.4% women. Mean RAID score was 4.3±2.2. With the ACR/EULAR Boolean definition, only 22 (6.1%) were in remission and 53 (14.8%) were in near-remission. In near-remission patients, the mean PGA was 3.3±1.5, and the mean RAID score was 3.6±1.8. The components of the RAID were mostly all >1/10 but specifically, physical well-being, fatigue, pain and functional assessment were more frequently >1/10 (94%, 89%, 87%, 83%) than sleep, coping or emotional well-being in these patients (79%, 79%, 74%, all p Conclusions The new definition of remission is extremely stringent and rarely attained for patients with long-standing RA. Near-remission is a more frequently achieved status. In this sample, psychological distress and lack of coping did not explain the raised PGA of near-remission, which was better explained by higher physical components of the RAID score. More work is needed to understand the patient perspective regarding remission. References Studenic P, et al. Ann Rheum Dis. 2012;71(10):1702-5. Sanderson T, et al. J Rheumatol 2011;38;191-194. Gossec L, et al. Ann Rheum Dis. 2011;70(6):935-42. Disclosure of Interest None Declared