Analysis of positive culture results of pathogens from neonatal septicemia cases in Guangdong Province.

Objective To survey the pathogenic bacteria and their drug resistance in neonatal septicemia cases in Guangdong for rational use of antibiotics in clinical treatment. Methods There 105 blood samples of neonatal septicemia cases from May 2007 to April 2009 in our hospital were cultured by Bact/ALE-RT3D120 automated blood culture system, the isolated strains were identified and their resistance to antibiotics was tested by VITEK -2 automicroscan. Results gram-positive cocci were the main pathogens,followed by gram-negative bacilli. The predominated strain was Staphylococcus epidermidis(28.6%),followed by Klebsiella pneumonia(17.1%),and the third is E. col(i14.3%). Gram-positive cocci was most sensitive to daifo -pristin,Zyvox and vancocin,while gram -negative bacilli was sensitive to amikacin and cefotetan. Conclusion There are increasing quantity of drug-resistant pathogens from blood samples of neonatal septicemia cases. Thus drug sensitivity test be carried for sake of rational use of anbiotics.