Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study.

Background The incidence of subacute stent thrombosis (SAT) within 30 days after stenting with a sirolimus-eluting stent (Cypher®) for acute myocardial infarction (AMI) was retrospectively compared to that with bare-metal stents (BMS). Methods and Results Among 559 lesions in 558 consecutive AMI from April 2003 to February 2006, the incidence of documented SAT after Cypher® implantation (2/276 lesions, 0.72%) was almost the same as for BMS (2 cases, 0.71%). Aspirin (81-100 mg/day) plus ticlopidine (200 mg/day) were administered continuously after admission in all 4 cases. Conclusion Documented SAT did not increase after stenting with Cypher ® for AMI under aspirin plus ticlopidine. (Circ J 2006; 70: 1091 - 1092)