Debneyol, a fungicidal sesquiterpene from tnv infected Nicotiana debneyi

Abstract An antifungal sesquiterpene diol, debneyol, has been isolated from tobacco necrosis virus-inoculated leaves of Nicotiana debneyi and a structure is proposed from chemical, spectroscopic and biogenetic evidence. In contrast to the related phytoalexin capsidiol which is fungistatic, debneyol appears to exhibit genuine fungicidal activity.