Lead Anti-obesity Compounds from Nature.
2020
: Background - Obesity has become a global disease, leading to the enhanced risk of metabolic syndrome which includes diabetes, cardiovascular disease, stroke, hypertension and certain cancers but it is difficult to control only by diet and exercise as they are difficult to implement. Objective- The objective of this review is to bring into light the active constituents that can be obtained from various natural sources which act as anti-obesity agents because with a global rise in the prevalence of obesity, an urgent need to prevent and control it has arisen. Method- For this review, we have compiled information about natural anti-obesity products, by an electronic search of the articles available on PubMed, Scopus and other internet sources for the duration of1975-2019and added my own research too. We have analyzed and organized data on various natural products in popular use and pharmacognostical and biological studies of them. Their mechanisms of action have also been studied. Conclusion-Consumption of diets comprising high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals.
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