Application of anesthesia with remifentanil in excision of polyp of vocal cord under self-retaining laryngoscope

Objective To compare the patients'stress reaction and palinesthesia of anesthesia with remifentanil and fentanyl in excision of polyp of vocal cord under self-retaining laryngoscope. Methods Eighty-six ASAⅠ-Ⅱ patients scheduled for polyp of vocal cord under self-retaining laryngoscope were randomly divided into two groups: fentanyl group (group F,n=43) and remifentanyl group (group R,n=43).Group F were induced with fentanyl,modazolam,propofol and succinylcholine chloride,maintained with fentanyl,propofol and succinylcholine chloride,while group R with remifentanil instead of fentanyl. The changes of SBP,DBP,MAP,HR, SpO2 were checked at different time point surround the operation. We recorded the anesthetize time and awake time, the quality of the anesthesia and side-effect of palinesthesia.Results The SBP,DBP,MAP and HR of group F were increased obviously after place self-retaining laryngoscope (P<0.01);The recovery time of group F was longer than that of group R (P<0.01);The incidences of postoperative nausea and vomit in group F were slightly higher than those in group R (P<0.05).Conclusions Compared with fentanyl,remifentanil can be used more safely and effectively in polypectomy of vocal cord. Key words: Remifentanil; Fentanil; Polyp of vocal cord; Anesthesia