Inhibition of Decarboxylase and Levels of Dopa and 3-O-Methyldopa: A Comparative Study of Benserazide versus Carbidopa in Rodents and of Madopar Standard versus Madopar HBS in Volunteers

M. Da Prada,R. Kettler,Gerhard Zürcher,R. Schaffner,W. Haefely

Inhibition of Decarboxylase and Levels of Dopa and 3-O-Methyldopa: A Comparative Study of Benserazide versus Carbidopa in Rodents and of Madopar Standard versus Madopar HBS in Volunteers

1987

M. Da Prada
R. Kettler
Gerhard Zürcher
R. Schaffner
W. Haefely

The combinations of benserazide and levodopa (1:4, Madopar®) and of carbidopa and levodopa (1:10 and 1:4, Sinemet®) are currently the most effective treatment of Parkinson’s disease. In the present co

Keywords:

Aromatic Amino Acid Decarboxylase Inhibitors
Levodopa
3-O-Methyldopa
Dopamine
Dihydroxyphenylalanine
Aromatic L-amino acid decarboxylase
Medicine
Pharmacology
Benserazide
Carbidopa
effective treatment

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