Experimental Salmonella dublin infection in calves

: Calves, aged 20 days, were experimentally infected with Salmonella dublin. The animals of one-group were treated at the rate of 6.10(8), and those of another--at 2.10(10) up to 4.10(10) live bacterial cells. The calves of the first group showed no clear clinical symptoms of a disease; neither did they manifest regular shedding of bacterial cells. The calves of the second group presented a typical clinical picture, with more regular shedding of bacteria through nasal discharges and the feces. After killing the animals Salmonella dublin organisms were found in all parenchymal organs and in the lymph nodes. Morphologically, the prevalence was established of inflammatory necrobiotic processes in the liver, with activation and proliferation of the sinus endothelium of the lymph nodes, and catarrhal inflammation of varying manifestation in the small intestine.