Effects of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Treated with Standardized Myrtol

Objective To investigate the effects of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) treated with standardized myrtol.Methods 86 patients were randomly divided into control group(group A,n = 44) and treatment group(group B,n = 42).All patients were treated with antibiotic and oxygen therapy.Standardized myrtol enteric coated soft capsules were given for group B but not for group A.After 14 days,the scores of clinical symptom,quality of life,blood gas analysis and pulmonary function were observed.Results The scores of clinical symptom after treatment were(4.6 ± 0.8) and(3.8 ± 0.9) in A and B groups respectively.And the quality of life scores were(7.2 ± 0.9) and(6.3 ± 1.1).There were significant differences between the two groups.The blood gas analysis and pulmonary function were significantly improved in the treatment group(P 0.05).Conclusion Standardized myrtol can improve blood gas,pulmonary function,clinical symptom and quality of life in AECOPD patients.The mechanism might be related on reducing air way inflammation and repairing airway mucus-ciliary clearance.