MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages

Vummidigiridhar Premkumar,Moul Dey,Ruth Dorn,Ilya Raskin

MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages

2010

Vummidigiridhar Premkumar
Moul Dey
Ruth Dorn
Ilya Raskin

Background Triptolide is a diterpene triepoxide from the Chinese medicinal plant Tripterygium wilfordii Hook F., with known anti-inflammatory, immunosuppressive and anti-cancer properties.

Keywords:

Toll-like receptor
Cell biology
Diterpene
Triptolide
Tripterygium wilfordii
Immune system
Signal transduction
Pharmacology
Biochemistry
Toll
Biology
Receptor
Proinflammatory cytokine
TLR4
TRIF
Downregulation and upregulation

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations