Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis.

C. A. Medeiros,R.F.C. Leitão,Rafael Nogueira de Macedo,D. R. M. M. Barboza,Antoniella S. Gomes,N. A. P. Nogueira,Nylane Maria Nunes de Alencar,Ronaldo A. Ribeiro,Gerly Anne de Castro Brito

Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis.

2011

C. A. Medeiros
R.F.C. Leitão
Rafael Nogueira de Macedo
D. R. M. M. Barboza
Antoniella S. Gomes
N. A. P. Nogueira
Nylane Maria Nunes de Alencar
Ronaldo A. Ribeiro
Gerly Anne de Castro Brito

Purpose Oral mucositis (OM) is a frequent side effect in patients with cancer. We investigate the effect of atorvastatin (ATV), a cholesterol-lowering drug, on OM induced by 5-fluorouracil (5-FU) in hamsters.

Keywords:

Biochemistry
Cancer
Side effect
Statin
Pharmacology
Fluorouracil
Atorvastatin
Mucositis
Stomatitis
Medicine
HMG-CoA reductase
Antimetabolite

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