A Mild, Efficient Method for the Oxidation of α-Diazo-β-hydroxyesters to α-Diazo-β-ketoesters.

Abstract A wide variety of α-diazo-β-ketoesters can be prepared in good overall yields via a two-step sequence involving addition of ethyl lithiodiazoacetate to aliphatic, aromatic, and conjugated aldehydes followed by mild oxidation with the Dess–Martin periodinane.