Assessment of successful percutaneous mitral commissurotomy by MRproANP and sCD146.

BACKGROUND: We studied the course of plasma concentrations of 4 cardiovascular biomarkers: natriuretic peptides (BNP, NT-proBNP; mid-regional (MR) pro-atrial NP); and soluble endothelial CD146 (sCD146), in patients with severe mitral valve stenosis undergoing percutaneous mitral commissurotomy (PMC) to identify potential markers of procedural success. METHODS: Biomarkers were tested in 40 patients the day before and the day after PMC. Success was defined as mitral valve area >/= 1.5 cm(2); or an increase of >/=0.5 cm2 in mitral valve area associated with echocardiographic mitral regurgitation

Keywords:

• Brain natriuretic peptide
• Percutaneous
• Hemodynamics
• Mitral valve stenosis
• Diabetes mellitus
• Cardiology
• Commissurotomy
• Medicine
• mitral regurgitation
• Mitral valve area
• Internal medicine
• Cardiac surgery
• Angiology
• Mitral valve

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