Bacterial Immunoglobulin (Ig)-Receptors: Past and Present Perspectives

The new contributions of this paper include the identification of bacterial Ig receptors as valuable reagents for the detection of Ig molecules in species of wild, domestic and laboratory animals. It is important to detect antibodies as markers of infection and zoonotic diseases. The techniques used to investigate the binding of the bacterial Ig receptors with immunoglobulins present in different specimens were established techniques such as ELISA and immunoblot analyses. In addition, the affinity chromatography allowed for the purification of immunoglobulins and their fragments. The use of commercially available conjugates of enzyme labelled proteins L, A, G and SpLA is discussed.