Mono-carbonyl curcumin analogue containing piperidone structure and application

The invention discloses a mono-carbonyl curcumin analogue containing a piperidone structure and application. The structure of the mono-carbonyl curcumin analogue is shown in the formula (I) or the formula (II); in the formula (I), R1 can be alkyl groups, naphthenic bases, benzyl groups, aroyl groups, substituent aroyl groups and sulfonyl groups optionally substituted by different substituent groups; in the formula (II), R2 can be piperazinyl, morpholinyl, pyrrolidyl and N, N-di-substituted alkyl optionally substituted by different substituent groups. A large amount of experimental study is performed on the technical field of mono-carbonyl curcumin analogues with substituent piperidone as a parent nucleus structure, a large amount of design, synthesis and pharmacological activity screening are performed on the mono-carbonyl curcumin analogues with substituent piperidone as the parent nucleus structure, one kind of single-carbonyl curcumin analogues with substituent piperidone as the parent nucleus structure are obtained, and the mono-carbonyl curcumin analogue containing the piperidone structure has the efficient and broad-spectrum anti-inflammatory application. Please see the formulae in the description.