HIV-1 genetic diversity to estimate time of infection and infer adherence to pre-exposure prophylaxis

Objective:To estimate time of HIV infection in participants from the Bangkok Tenofovir Study (BTS) with daily oral tenofovir disoproxil fumarate (TDF) for preexposure prophylaxis (PrEP) and relate infection with adherence patterns.Design:We used the diversity structure of the virus population at the