CHARACTERISTICS OF GHRELINPOSITIVE CELLS IN EXTRAHEPATIC BILE DUCTS OF THE RAT

Ghrelin is a newly discovered hormone that associated with the metabolism and produced mostly by endocrine cells in the stomach fundus. There are data that there is a ghrelin production at other places: testis, pancreas, thyroid gland. The aim of this investigation is to discover ghrelinpositive endocrine cells in the extrahepatic bile ducts of the rat. We applied immunohistochemical methods and antibodies Ghrelin (H- 40) SC- 50 297, Company Santa Cruz, USA to the bile mucosa. We visualized results with detection system Daco - En Vision FLEX - Mini Kit. Rare grelinpositive cells were visualized in the mucosa of the extrahepatic bile ducts.