Lipid Composition of Different Brain Regions in Patients with Alzheimer’s Disease and Multi-Infarct Dementia

In membranes phospholipids are in a highly dynamic state, altering membrane functions and participating actively in the regulation of cell metabolism. Changes of the phos-pholipid head group as well as heterogenous acyl chain composition influence and regulate the structure, stability and fluidity of the membranes. Phospholipids serve as im portant mediators in the transduction of extracellular signals.