Ultrahigh hydrostatic pressure extraction of flavonoids from Epimedium koreanum Nakai
2011
Herba Epimedii is one of the most famous Chinese herbal medicines listed in the Pharmacopoeia of the People's
Republic of China, as one of the representatives of traditional Chinese herb, it has been widely applied in the field of
invigorate the kidney and strengthen 'Yang'. The attention to Epimedium extract has more and more increased in recent
years. In this work, a novel extraction technique, ultra-high hydrostatic pressure extraction (UPE) technology was
applied to extract the total flavonoids of E. koreanum . Three factors (pressure, ethanol concentration and extraction time)
were chosen as the variables of extraction experiments, and the optimum UPE conditions were pressure 350 MPa;
ethanol concentration 50% (v/v); extraction time 5 min. Compared with Supercritical CO 2 extraction, Reflux extraction
and Ultrasonic-assisted extraction, UPE has excellent advantages (shorter extraction time, higher yield, better antioxidant
activity, lower energy consumption and eco-friendly).
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