In Vitro and In Vivo Renoprotective Effects of Telbivudine in Chronic Hepatitis B Patients Receiving Nucleotide Analogue

Lung-Yi Mak,Sze-Hang Liu,Desmond Y.H. Yap,Wai-Kay Seto,Danny Ka-Ho Wong,James Fung,Tak Mao Chan,Ching-Lung Lai,Man-Fung Yuen

In Vitro and In Vivo Renoprotective Effects of Telbivudine in Chronic Hepatitis B Patients Receiving Nucleotide Analogue

2019

Lung-Yi Mak
Sze-Hang Liu
Desmond Y.H. Yap
Wai-Kay Seto
Danny Ka-Ho Wong
James Fung
Tak Mao Chan
Ching-Lung Lai
Man-Fung Yuen

Aim Renal toxicity of adefovir disoproxil (ADV) and tenofovir disoproxil fumarate (TDF) is a significant concern in chronic hepatitis B (CHB) patients. Early observational clinical data suggested that telbivudine (LdT) might have renoprotective effects.

Keywords:

Endocrinology
Internal medicine
Diabetes mellitus
Hepatitis B
Medicine
Toxicity
Nephrotoxicity
Telbivudine
In vivo
Pharmacology
Adefovir
In vitro
Gastroenterology
Renal function
Kidney disease
Hepatology
Adjuvant therapy
Lamivudine

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