Reductive Electrochemical Detection for Capillary Electrophoresis

A system has been developed for reductive electrochemical detection with capillary electrophoresis. The instrumental setup is much simpler than that of reductive liquid chromatography/ electrochemistry (LCEC). The new method also possesses major advantages over LC-based methods in terms of a legs complicated deoxygenation system and shorter deoxygenation times. Concentration detection limits were similar to those reported for reductive LCEC. Mass detection limits for anthraquinone-2-carboxylic acid and (dinitropbenyl)-γ-aminobutyric acid were 1.3 and 1.6 μmoL respectively, at a S/N of 2. The reproducibility of the signal for a 9.8-μmol anthraquinone-2-carboxylic acid injection yielded a relative standard deviation of 6.2%