Sustainable Suzuki-Miyaura Reaction Catalyzed by Pd(OAc)2 Immobilized on Reversed-Phase Alumina

Employing Pd(OAc) 2 immobilized on amorphous N, N-diethylaminopropyl alumina, Suzuki-Miyaura coupling of aryl halide with arylboronic acid was realized in 50% aqueous ethanol at room temperature, which enabled repeated use up to four times in 96% average yield and achieved a turnover number of 15 000.