Cerebral Ventricular Volumetry in Pediatric Neuroimaging

A prospective NIH funded study examines the effects of early brain damage on selective aspects of cognitive development in children. We describe an efficient method to segment and visualize the intracerebral fluid spaces in children and adults based on MRI and to quantify ventricular volumes which is (a) robust (for normal and pathological anatomy), (b) reproducible (less than 2 % relative variation), and (c) fast (less than 5 min for image analysis).