Haemolytic-uraemic syndrome in patients with Crohn's disease.

mimic Crohn’s disease or ulcerative colitis [2,3]. We of the platelet count, disappearance of the microangidescribe here the clinical course of two patients with opathic anaemia and a normal renal function (serum HUS occurring several years after the initial diagnosis creatinine 115 mmol/ l). of Crohn’s disease was established. One patient had Shiga-like toxins detected in the stools. Both patients had complete renal remission. We suggest that Crohn’s disease can be listed as a predisposing factor for the Case report 2 development of HUS. The patient was a 24-year-old young man. Two years before admission, he had bloody diarrhoea, abdominal Case report 1 pain and 10-kg weight loss. He was admitted to another hospital where the diagnosis of Crohn’s disease was A 53-year-old man was admitted for acute renal failure. made after clinical, radiological, and pathological tests. Seven years before admission, he presented with per- Ileal biopsy was considered typical of the disease. The sistent bloody diarrhoea and abdominal pain. The symptoms resumed after treatment with corticosteroids diagnosis of Crohn’s disease was made on clinical and and mesalazine. Two months before admission, he had pathological data (ileal biopsy), and salazopyrin was a new bout of diarrhoea. Colonoscopic examination prescribed. Between the initial diagnosis of Crohn’s showed diVuse inflammatory activity and mesalazine disease and admission for acute renal failure, he and amoxycillin were given. Gastrointestinal symptoms suVered three diVerent episodes of severe abdominal persisted and he was admitted for bloody diarrhoea pain. At admission, he presented with anorexia, dia- and severe oliguria. At entry, blood pressure was rrhoea, abdominal pain, and confusion. Blood pressure 135/65 mmHg, temperature was 37°C. He complained