Synthesis of Desthiobiotin

S. I. Zavyalov,E. P. Gracheva,N.A. Rodionova,Z. S. Volkova,Yu. B. Vol'kenshtein,P. A. Stankevich,U. Ya. Mikstais,S. Ya. Miksta,V V Filippov

Synthesis of Desthiobiotin

1973

S. I. Zavyalov
E. P. Gracheva
N.A. Rodionova
Z. S. Volkova
Yu. B. Vol'kenshtein
P. A. Stankevich
U. Ya. Mikstais
S. Ya. Miksta
V V Filippov

A method was developed for the preparation of cis-desthiobiotin by the hydrogenation of the ethyl ester of ketodehydrodesthiobiotin over skeletal nickel catalyst in alcohol in the presence of NaOH.

Keywords:

Catalysis
Organic chemistry
Inorganic chemistry
Alcohol
Chemistry
Nickel
ethyl ester
nickel catalyst

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