Isolation of CpG Island Fragments
1996
An anonymous human DNA fragment R16-2, which was isolated as a possible CpG island fragment by the segregation of partly melted molecules method (SPM), was found to contain a putative promoter region of the prostacyclin synthase gene. Based on this data, it is suggested that combined use of the SPM technique and the database match enables a fine characterization of the regulatory region of many genes.
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