Fluorescent probes for ecto-5ʹ-nucleotidase (CD73)

Constanze C. Schmies,Georg Rolshoven,Riham M. Idris,Karolina Losenkova,Christian Renn,Laura Schäkel,Haneen Al-Hroub,Yulu Wang,Francesca Garofano,Ingo G.H. Schmidt-Wolf,Herbert Zimmermann,Gennady G. Yegutkin,Christa E. Müller

Fluorescent probes for ecto-5ʹ-nucleotidase (CD73)

2020

Constanze C. Schmies
Georg Rolshoven
Riham M. Idris
Karolina Losenkova
Christian Renn
Laura Schäkel
Haneen Al-Hroub
Yulu Wang
Francesca Garofano
Ingo G.H. Schmidt-Wolf
Herbert Zimmermann
Gennady G. Yegutkin
Christa E. Müller

Ecto-5′-nucleotidase (CD73) catalyzes the hydrolysis of AMP to anti-inflammatory, immunosuppressive adenosine. It is expressed on vascular endothelial, epithelial, and also numerous cancer cells wh...

Keywords:

Biochemistry
Chemistry
Nucleotidase
Fluorescence

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